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Urease is an essential component of the acid response network of Staphylococcus aureus and is required for a persistent murine kidney infection
Staphylococcus aureus causes acute and chronic infections resulting in significant morbidity. Urease, an enzyme that generates NH(3) and CO(2) from urea, is key to pH homeostasis in bacterial pathogens under acidic stress and nitrogen limitation. However, the function of urease in S. aureus niche co...
Autores principales: | Zhou, Chunyi, Bhinderwala, Fatema, Lehman, McKenzie K., Thomas, Vinai C., Chaudhari, Sujata S., Yamada, Kelsey J., Foster, Kirk W., Powers, Robert, Kielian, Tammy, Fey, Paul D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343930/ https://www.ncbi.nlm.nih.gov/pubmed/30608981 http://dx.doi.org/10.1371/journal.ppat.1007538 |
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