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Economic burden of dengue in Indonesia
BACKGROUND: Dengue is associated with significant economic expenditure and it is estimated that the Asia Pacific region accounts for >50% of the global cost. Indonesia has one of the world’s highest dengue burdens; Aedes aegypti and Aedes albopictus are the primary and secondary vectors. In the a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343936/ https://www.ncbi.nlm.nih.gov/pubmed/30629593 http://dx.doi.org/10.1371/journal.pntd.0007038 |
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author | Nadjib, Mardiati Setiawan, Ery Putri, Septiara Nealon, Joshua Beucher, Sophie Hadinegoro, Sri Rezeki Permanasari, Vetty Yulianty Sari, Kurnia Wahyono, Tri Yunis Miko Kristin, Erna Wirawan, Dewa Nyoman Thabrany, Hasbullah |
author_facet | Nadjib, Mardiati Setiawan, Ery Putri, Septiara Nealon, Joshua Beucher, Sophie Hadinegoro, Sri Rezeki Permanasari, Vetty Yulianty Sari, Kurnia Wahyono, Tri Yunis Miko Kristin, Erna Wirawan, Dewa Nyoman Thabrany, Hasbullah |
author_sort | Nadjib, Mardiati |
collection | PubMed |
description | BACKGROUND: Dengue is associated with significant economic expenditure and it is estimated that the Asia Pacific region accounts for >50% of the global cost. Indonesia has one of the world’s highest dengue burdens; Aedes aegypti and Aedes albopictus are the primary and secondary vectors. In the absence of local data on disease cost, this study estimated the annual economic burden during 2015 of both hospitalized and ambulatory dengue cases in Indonesia. METHODS: Total 2015 dengue costs were calculated using both prospective and retrospective methods using data from public and private hospitals and health centres in three provinces: Yogyakarta, Bali and Jakarta. Direct costs were extracted from billing systems and claims; a patient survey captured indirect and out-of-pocket costs at discharge and 2 weeks later. Adjustments across sites based on similar clinical practices and healthcare landscapes were performed to fill gaps in cost estimates. The national burden of dengue was extrapolated from provincial data using data from the three sites and applying an empirically-derived epidemiological expansion factor. RESULTS: Total direct and indirect costs per dengue case assessed at Yogyakarta, Bali and Jakarta were US$791, US$1,241 and US$1,250, respectively. Total 2015 economic burden of dengue in Indonesia was estimated at US$381.15 million which comprised US$355.2 million for hospitalized and US$26.2 million for ambulatory care cases. CONCLUSION: Dengue imposes a substantial economic burden for Indonesian public payers and society. Complemented with an appropriate weighting method and by accounting for local specificities and practices, these data may support national level public health decision making for prevention/control of dengue in public health priority lists. |
format | Online Article Text |
id | pubmed-6343936 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-63439362019-02-01 Economic burden of dengue in Indonesia Nadjib, Mardiati Setiawan, Ery Putri, Septiara Nealon, Joshua Beucher, Sophie Hadinegoro, Sri Rezeki Permanasari, Vetty Yulianty Sari, Kurnia Wahyono, Tri Yunis Miko Kristin, Erna Wirawan, Dewa Nyoman Thabrany, Hasbullah PLoS Negl Trop Dis Research Article BACKGROUND: Dengue is associated with significant economic expenditure and it is estimated that the Asia Pacific region accounts for >50% of the global cost. Indonesia has one of the world’s highest dengue burdens; Aedes aegypti and Aedes albopictus are the primary and secondary vectors. In the absence of local data on disease cost, this study estimated the annual economic burden during 2015 of both hospitalized and ambulatory dengue cases in Indonesia. METHODS: Total 2015 dengue costs were calculated using both prospective and retrospective methods using data from public and private hospitals and health centres in three provinces: Yogyakarta, Bali and Jakarta. Direct costs were extracted from billing systems and claims; a patient survey captured indirect and out-of-pocket costs at discharge and 2 weeks later. Adjustments across sites based on similar clinical practices and healthcare landscapes were performed to fill gaps in cost estimates. The national burden of dengue was extrapolated from provincial data using data from the three sites and applying an empirically-derived epidemiological expansion factor. RESULTS: Total direct and indirect costs per dengue case assessed at Yogyakarta, Bali and Jakarta were US$791, US$1,241 and US$1,250, respectively. Total 2015 economic burden of dengue in Indonesia was estimated at US$381.15 million which comprised US$355.2 million for hospitalized and US$26.2 million for ambulatory care cases. CONCLUSION: Dengue imposes a substantial economic burden for Indonesian public payers and society. Complemented with an appropriate weighting method and by accounting for local specificities and practices, these data may support national level public health decision making for prevention/control of dengue in public health priority lists. Public Library of Science 2019-01-10 /pmc/articles/PMC6343936/ /pubmed/30629593 http://dx.doi.org/10.1371/journal.pntd.0007038 Text en © 2019 Nadjib et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Nadjib, Mardiati Setiawan, Ery Putri, Septiara Nealon, Joshua Beucher, Sophie Hadinegoro, Sri Rezeki Permanasari, Vetty Yulianty Sari, Kurnia Wahyono, Tri Yunis Miko Kristin, Erna Wirawan, Dewa Nyoman Thabrany, Hasbullah Economic burden of dengue in Indonesia |
title | Economic burden of dengue in Indonesia |
title_full | Economic burden of dengue in Indonesia |
title_fullStr | Economic burden of dengue in Indonesia |
title_full_unstemmed | Economic burden of dengue in Indonesia |
title_short | Economic burden of dengue in Indonesia |
title_sort | economic burden of dengue in indonesia |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343936/ https://www.ncbi.nlm.nih.gov/pubmed/30629593 http://dx.doi.org/10.1371/journal.pntd.0007038 |
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