Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge

The development of a sterilizing vaccine against malaria remains one of the highest priorities for global health research. While sporozoite vaccines targeting the pre-erythrocytic stage show great promise, it has not been possible to maintain efficacy long-term, likely due to an inability of these v...

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Detalles Bibliográficos
Autores principales: Hansen, Scott G., Womack, Jennie, Scholz, Isabel, Renner, Andrea, Edgel, Kimberly A., Xu, Guangwu, Ford, Julia C., Grey, Mikayla, St. Laurent, Brandyce, Turner, John M., Planer, Shannon, Legasse, Al W., Richie, Thomas L., Aguiar, Joao C., Axthelm, Michael K., Villasante, Eileen D., Weiss, Walter, Edlefsen, Paul T., Picker, Louis J., Früh, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343944/
https://www.ncbi.nlm.nih.gov/pubmed/30673723
http://dx.doi.org/10.1371/journal.pone.0210252

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