Pigmented odontogenic keratocyst: Report of a rare case and review of the literature

Pigmented odontogenic keratocyst (OKC) is very rare and its etiology remains uncertain. To the best of our knowledge, only 9 cases of pigmented OKC have been published in English-language literature. This report describes a pigmented OKC in a 14-year-old black male patient. Radiographically, the les...

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Detalles Bibliográficos
Autores principales: Rodrigues-Fernandes, Carla-Isabelly, Bonan, Paulo-Rogério-Ferreti, Carvalho, Elaine-Judite-de Amorim, Sánchez-Romero, Celeste, de Almeida, Oslei-Paes, Perez, Danyel-Elias-da Cruz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343978/
https://www.ncbi.nlm.nih.gov/pubmed/30697383
http://dx.doi.org/10.4317/jced.55134
Descripción
Sumario:Pigmented odontogenic keratocyst (OKC) is very rare and its etiology remains uncertain. To the best of our knowledge, only 9 cases of pigmented OKC have been published in English-language literature. This report describes a pigmented OKC in a 14-year-old black male patient. Radiographically, the lesion appeared as a well-circumscribed, unilocular, and radiolucent image. A surgical excision was performed. Histopathological examination revealed an OKC. Additionally, a brownish, sparsed, intracytoplasmic pigmentation was observed in the basal cell layer, which was positive for Fontana-Masson staining. Immunohistochemistry reactions revealed positive dendritic cells for S-100 protein, HMB45 and Melan A. No clinical and imaging signs of recurrence were observed after 24 months. In conclusion, melanin apparently does not represent a factor for distinct biological behavior in OKC. Key words:Melanin, melanocytes, odontogenic cyst, odontogenic keratocyst, pigmented.

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