Cargando…
Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD
The AMP-activated protein kinase (AMPK) is a highly conserved master regulator of metabolism, whose activation has been proposed to be therapeutically beneficial for the treatment of several metabolic diseases, including nonalcoholic fatty liver disease (NAFLD). NAFLD, characterized by excessive acc...
Autores principales: | Garcia, Daniel, Hellberg, Kristina, Chaix, Amandine, Wallace, Martina, Herzig, Sébastien, Badur, Mehmet G., Lin, Terry, Shokhirev, Maxim N., Pinto, Antonio F.M., Ross, Debbie S., Saghatelian, Alan, Panda, Satchidananda, Dow, Lukas E., Metallo, Christian M., Shaw, Reuben J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344045/ https://www.ncbi.nlm.nih.gov/pubmed/30605676 http://dx.doi.org/10.1016/j.celrep.2018.12.036 |
Ejemplares similares
-
The circadian coordination of cell biology
por: Chaix, Amandine, et al.
Publicado: (2016) -
Sex- and age-dependent outcomes of 9-hour time-restricted feeding of a Western high-fat high-sucrose diet in C57BL/6J mice
por: Chaix, Amandine, et al.
Publicado: (2021) -
AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation
por: Van Nostrand, Jeanine L., et al.
Publicado: (2020) -
Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism
por: Zarrinpar, Amir, et al.
Publicado: (2018) -
AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes
por: Young, Nathan P., et al.
Publicado: (2016)