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Comparison of in vitro static and dynamic assays to evaluate the efficacy of an antimicrobial drug combination against Staphylococcus aureus

An easily implementable strategy to reduce treatment failures in severe bacterial infections is to combine already available antibiotics. However, most in vitro combination assays are performed by exposing standard bacterial inocula to constant concentrations of antibiotics over less than 24h, which...

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Detalles Bibliográficos
Autores principales: Broussou, Diane C., Toutain, Pierre-Louis, Woehrlé, Frédérique, El Garch, Farid, Bousquet-Melou, Alain, Ferran, Aude A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344103/
https://www.ncbi.nlm.nih.gov/pubmed/30673774
http://dx.doi.org/10.1371/journal.pone.0211214