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A simplified scoring system for the prediction of pancreatoduodenectomy's complications: An observational study

To assess the efficiency of several previous scoring systems in the prediction of postoperative complications of pancreatoduodenectomy (PCPD) and to explore a new simplified scoring system for PCPD prediction. All 183 consecutive patients scheduled for PD from 2010 to 2017 in the Second Affiliated H...

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Autores principales: Chen, Long, Su, Dai-Wen, Zhang, Fan, Shen, Jun-Yi, Zhang, Yan-Hong, Wang, Yun-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344119/
https://www.ncbi.nlm.nih.gov/pubmed/30608435
http://dx.doi.org/10.1097/MD.0000000000013969
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author Chen, Long
Su, Dai-Wen
Zhang, Fan
Shen, Jun-Yi
Zhang, Yan-Hong
Wang, Yun-Bing
author_facet Chen, Long
Su, Dai-Wen
Zhang, Fan
Shen, Jun-Yi
Zhang, Yan-Hong
Wang, Yun-Bing
author_sort Chen, Long
collection PubMed
description To assess the efficiency of several previous scoring systems in the prediction of postoperative complications of pancreatoduodenectomy (PCPD) and to explore a new simplified scoring system for PCPD prediction. All 183 consecutive patients scheduled for PD from 2010 to 2017 in the Second Affiliated Hospital of Chongqing Medical University were collected retrospectively. The area under the curve (AUC) for the prediction of PCPD was calculated for POSSUM, E-PASS, APACHE-II, and APACHE-III, which were used to test the efficiency of PCPD prediction. The independent risk factors included in the new scoring system were determined by univariate analysis and a logistic regression model. Next, the prediction efficiency was validated. The results of the univariate analysis showed that such variables as male sex, weight, WBC, serum sodium, arterial pH, postoperative 24 hours urine output, and operation time were influence factors for postoperative complications (P <.05). Arterial pH, serum sodium, postoperative 24 hours urine output, and WBC were independent risk factors of postoperative complications based on the logistic regression analysis (P <.05). The AUC of the novel scoring system for PCPD prediction was 85.4%. The proposed scoring system might be a more effective tool for predicting PCPD compared with previous multipurpose scoring systems.
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spelling pubmed-63441192019-02-04 A simplified scoring system for the prediction of pancreatoduodenectomy's complications: An observational study Chen, Long Su, Dai-Wen Zhang, Fan Shen, Jun-Yi Zhang, Yan-Hong Wang, Yun-Bing Medicine (Baltimore) Research Article To assess the efficiency of several previous scoring systems in the prediction of postoperative complications of pancreatoduodenectomy (PCPD) and to explore a new simplified scoring system for PCPD prediction. All 183 consecutive patients scheduled for PD from 2010 to 2017 in the Second Affiliated Hospital of Chongqing Medical University were collected retrospectively. The area under the curve (AUC) for the prediction of PCPD was calculated for POSSUM, E-PASS, APACHE-II, and APACHE-III, which were used to test the efficiency of PCPD prediction. The independent risk factors included in the new scoring system were determined by univariate analysis and a logistic regression model. Next, the prediction efficiency was validated. The results of the univariate analysis showed that such variables as male sex, weight, WBC, serum sodium, arterial pH, postoperative 24 hours urine output, and operation time were influence factors for postoperative complications (P <.05). Arterial pH, serum sodium, postoperative 24 hours urine output, and WBC were independent risk factors of postoperative complications based on the logistic regression analysis (P <.05). The AUC of the novel scoring system for PCPD prediction was 85.4%. The proposed scoring system might be a more effective tool for predicting PCPD compared with previous multipurpose scoring systems. Wolters Kluwer Health 2019-01-04 /pmc/articles/PMC6344119/ /pubmed/30608435 http://dx.doi.org/10.1097/MD.0000000000013969 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle Research Article
Chen, Long
Su, Dai-Wen
Zhang, Fan
Shen, Jun-Yi
Zhang, Yan-Hong
Wang, Yun-Bing
A simplified scoring system for the prediction of pancreatoduodenectomy's complications: An observational study
title A simplified scoring system for the prediction of pancreatoduodenectomy's complications: An observational study
title_full A simplified scoring system for the prediction of pancreatoduodenectomy's complications: An observational study
title_fullStr A simplified scoring system for the prediction of pancreatoduodenectomy's complications: An observational study
title_full_unstemmed A simplified scoring system for the prediction of pancreatoduodenectomy's complications: An observational study
title_short A simplified scoring system for the prediction of pancreatoduodenectomy's complications: An observational study
title_sort simplified scoring system for the prediction of pancreatoduodenectomy's complications: an observational study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344119/
https://www.ncbi.nlm.nih.gov/pubmed/30608435
http://dx.doi.org/10.1097/MD.0000000000013969
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