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NEO6860, modality-selective TRPV1 antagonist: a randomized, controlled, proof-of-concept trial in patients with osteoarthritis knee pain

INTRODUCTION: NEO6860 is a TRPV1 antagonist when activated by capsaicin but not by heat or pH, developed to relieve pain without the adverse events reported with non–modality-selective TRPV1 antagonists. OBJECTIVE: The primary Objective of this study was to evaluate the analgesic efficacy and safety...

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Detalles Bibliográficos
Autores principales: Arsenault, Pierre, Chiche, Dan, Brown, William, Miller, Jeffrey, Treister, Roi, Leff, Richard, Walker, Philippe, Katz, Nathaniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344137/
https://www.ncbi.nlm.nih.gov/pubmed/30706039
http://dx.doi.org/10.1097/PR9.0000000000000696