Discovery of a New Natural Product and a Deactivation of a Quorum Sensing System by Culturing a “Producer” Bacterium With a Heat-Killed “Inducer” Culture

Herein we describe a modified bacterial culture methodology as a tool to discover new natural products via supplementing actinomycete fermentation media with autoclaved cultures of “inducer” microbes. Using seven actinomycetes and four inducer microbes, we detected 28 metabolites that were induced i...

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Detalles Bibliográficos
Autores principales: Liang, Libang, Sproule, Amanda, Haltli, Brad, Marchbank, Douglas H., Berrué, Fabrice, Overy, David P., McQuillan, Kate, Lanteigne, Martin, Duncan, Noelle, Correa, Hebelin, Kerr, Russell G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344404/
https://www.ncbi.nlm.nih.gov/pubmed/30705672
http://dx.doi.org/10.3389/fmicb.2018.03351

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