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Concomitant Enhancement of HIV-1 Replication Potential and Neutralization-Resistance in Concert With Three Adaptive Mutations in Env V1/C2/C4 Domains
HIV-1 Env protein functions in the entry process and is the target of neutralizing antibodies. Its intrinsically high mutation rate is certainly one of driving forces for persistence/survival in hosts. For optimal replication in various environments, HIV-1 Env must continue to adapt and evolve throu...
Autores principales: | Doi, Naoya, Yokoyama, Masaru, Koma, Takaaki, Kotani, Osamu, Sato, Hironori, Adachi, Akio, Nomaguchi, Masako |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344430/ https://www.ncbi.nlm.nih.gov/pubmed/30705669 http://dx.doi.org/10.3389/fmicb.2019.00002 |
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