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Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues

African swine fever virus (ASFV) is contagious and can cause highly lethal disease in pigs. ASFV DNA ligase (AsfvLIG) is one of the most error-prone ligases identified to date; it catalyzes DNA joining reaction during DNA repair process of ASFV and plays important roles in mutagenesis of the viral g...

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Detalles Bibliográficos
Autores principales:	Chen, Yiqing, Liu, Hehua, Yang, Chun, Gao, Yanqing, Yu, Xiang, Chen, Xi, Cui, Ruixue, Zheng, Lina, Li, Suhua, Li, Xuhang, Ma, Jinbiao, Huang, Zhen, Li, Jixi, Gan, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344480/ https://www.ncbi.nlm.nih.gov/pubmed/30674878 http://dx.doi.org/10.1038/s41467-019-08296-w

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