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Generation of H7N9-specific human polyclonal antibodies from a transchromosomic goat (caprine) system

To address the unmet needs for human polyclonal antibodies both as therapeutics and diagnostic reagents, building upon our previously established transchromosomic (Tc) cattle platform, we report herein the development of a Tc goat system expressing human polyclonal antibodies in their sera. In the T...

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Detalles Bibliográficos
Autores principales:	Wu, Hua, Fan, Zhiqiang, Brandsrud, Michelle, Meng, Qinggang, Bobbitt, Molly, Regouski, Misha, Stott, Rusty, Sweat, Alexis, Crabtree, Jackelyn, Hogan, Robert J., Tripp, Ralph A., Wang, Zhongde, Polejaeva, Irina A., Sullivan, Eddie J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344498/ https://www.ncbi.nlm.nih.gov/pubmed/30675003 http://dx.doi.org/10.1038/s41598-018-36961-5

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