Hypercapnia Alters Alveolar Epithelial Repair by a pH-Dependent and Adenylate Cyclase-Mediated Mechanism

Lung cell injury and repair is a hallmark of the acute respiratory distress syndrome (ARDS). Lung protective mechanical ventilation strategies in these patients may lead to hypercapnia (HC). Although HC has been explored in the clinical context of ARDS, its effect upon alveolar epithelial cell (AEC)...

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Detalles Bibliográficos
Autores principales: Cortes-Puentes, Gustavo A., Westerly, Blair, Schiavo, Dante, Wang, Shaohua, Stroetz, Randolph, Walters, Bruce, Hubmayr, Rolf D., Oeckler, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344503/
https://www.ncbi.nlm.nih.gov/pubmed/30674971
http://dx.doi.org/10.1038/s41598-018-36951-7

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