Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor(−/−) Mice Improves Indices of Cardiometabolic Disease

Obesity increases the risk for cardiometabolic diseases. N-acyl phosphatidylethanolamines (NAPEs) are precursors of N-acylethanolamides, which are endogenous lipid satiety factors. Incorporating engineered bacteria expressing NAPEs into the gut microbiota retards development of diet induced obesity...

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Detalles Bibliográficos
Autores principales: May-Zhang, Linda S., Chen, Zhongyi, Dosoky, Noura S., Yancey, Patricia G., Boyd, Kelli L., Hasty, Alyssa H., Linton, MacRae F., Davies, Sean S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344515/
https://www.ncbi.nlm.nih.gov/pubmed/30674978
http://dx.doi.org/10.1038/s41598-018-37373-1

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