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Sex-specific moderation by lifestyle and psychosocial factors on the genetic contributions to adiposity in 112,151 individuals from UK Biobank

Evidence suggests that lifestyle factors, e.g. physical activity, moderate the manifestation of genetic susceptibility to obesity. The present study uses UK Biobank data to investigate interaction between polygenic scores (PGS) for two obesity indicators, and lifestyle and psychosocial factors in th...

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Detalles Bibliográficos
Autores principales: Calvin, Catherine M., Hagenaars, Saskia P., Gallacher, John, Harris, Sarah E., Davies, Gail, Liewald, David C., Gale, Catharine R., Deary, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344557/
https://www.ncbi.nlm.nih.gov/pubmed/30675005
http://dx.doi.org/10.1038/s41598-018-36629-0