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Parieto-frontal mechanisms underlying observation of complex hand-object manipulation

The observation of actions performed by others is believed to activate the Action Observation Network (AON). Previous evidence suggests that subjects with a specific motor skill show increased activation of the AON during observation of the same skill. The question arises regarding which modulation...

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Autores principales: Errante, Antonino, Fogassi, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344645/
https://www.ncbi.nlm.nih.gov/pubmed/30674948
http://dx.doi.org/10.1038/s41598-018-36640-5
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author Errante, Antonino
Fogassi, Leonardo
author_facet Errante, Antonino
Fogassi, Leonardo
author_sort Errante, Antonino
collection PubMed
description The observation of actions performed by others is believed to activate the Action Observation Network (AON). Previous evidence suggests that subjects with a specific motor skill show increased activation of the AON during observation of the same skill. The question arises regarding which modulation of the AON occurs during observation of novel complex manipulative actions that are beyond the personal motor repertoire. To address this issue, we carried out a functional MRI study in which healthy volunteers without specific hand motor skills observed videos displaying hand-object manipulation executed by an expert with high manual dexterity, by an actor with intermediate ability or by a naïve subject. The results showed that the observation of actions performed by a naïve model produced stronger activation in a dorso-medial parieto-premotor circuit including the superior parietal lobule and dorsal premotor cortex, compared to observation of an expert actor. Functional connectivity analysis comparing the observation of the naïve model with that of the expert model, revealed increased connectivity between dorsal areas of the AON. This suggests a possible distinction between ventral and dorsal brain circuits involved in the processing of different aspects of action perception, such as kinematics and final action goal.
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spelling pubmed-63446452019-01-28 Parieto-frontal mechanisms underlying observation of complex hand-object manipulation Errante, Antonino Fogassi, Leonardo Sci Rep Article The observation of actions performed by others is believed to activate the Action Observation Network (AON). Previous evidence suggests that subjects with a specific motor skill show increased activation of the AON during observation of the same skill. The question arises regarding which modulation of the AON occurs during observation of novel complex manipulative actions that are beyond the personal motor repertoire. To address this issue, we carried out a functional MRI study in which healthy volunteers without specific hand motor skills observed videos displaying hand-object manipulation executed by an expert with high manual dexterity, by an actor with intermediate ability or by a naïve subject. The results showed that the observation of actions performed by a naïve model produced stronger activation in a dorso-medial parieto-premotor circuit including the superior parietal lobule and dorsal premotor cortex, compared to observation of an expert actor. Functional connectivity analysis comparing the observation of the naïve model with that of the expert model, revealed increased connectivity between dorsal areas of the AON. This suggests a possible distinction between ventral and dorsal brain circuits involved in the processing of different aspects of action perception, such as kinematics and final action goal. Nature Publishing Group UK 2019-01-23 /pmc/articles/PMC6344645/ /pubmed/30674948 http://dx.doi.org/10.1038/s41598-018-36640-5 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Errante, Antonino
Fogassi, Leonardo
Parieto-frontal mechanisms underlying observation of complex hand-object manipulation
title Parieto-frontal mechanisms underlying observation of complex hand-object manipulation
title_full Parieto-frontal mechanisms underlying observation of complex hand-object manipulation
title_fullStr Parieto-frontal mechanisms underlying observation of complex hand-object manipulation
title_full_unstemmed Parieto-frontal mechanisms underlying observation of complex hand-object manipulation
title_short Parieto-frontal mechanisms underlying observation of complex hand-object manipulation
title_sort parieto-frontal mechanisms underlying observation of complex hand-object manipulation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344645/
https://www.ncbi.nlm.nih.gov/pubmed/30674948
http://dx.doi.org/10.1038/s41598-018-36640-5
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