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Detection of influenza A(H3N2) viruses exhibiting reduced susceptibility to the novel cap-dependent endonuclease inhibitor baloxavir in Japan, December 2018
The novel cap-dependent endonuclease inhibitor baloxavir marboxil was approved for the treatment of influenza virus infection in Japan in February 2018. Two influenza A(H3N2) viruses carrying an I38T substitution in the polymerase acidic subunit (PA) were detected in baloxavir-treated children in De...
Autores principales: | Takashita, Emi, Kawakami, Chiharu, Morita, Hiroko, Ogawa, Rie, Fujisaki, Seiichiro, Shirakura, Masayuki, Miura, Hideka, Nakamura, Kazuya, Kishida, Noriko, Kuwahara, Tomoko, Mitamura, Keiko, Abe, Takashi, Ichikawa, Masataka, Yamazaki, Masahiko, Watanabe, Shinji, Odagiri, Takato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Centre for Disease Prevention and Control (ECDC)
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344841/ https://www.ncbi.nlm.nih.gov/pubmed/30670142 http://dx.doi.org/10.2807/1560-7917.ES.2019.24.3.1800698 |
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