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Dynamic protein–RNA interactions in mediating splicing catalysis
The spliceosome is assembled via sequential interactions of pre-mRNA with five small nuclear RNAs and many proteins. Recent determination of cryo-EM structures for several spliceosomal complexes has provided deep insights into interactions between spliceosomal components and structural changes of th...
Autores principales: | Chung, Che-Sheng, Tseng, Chi-Kang, Lai, Yung-Hua, Wang, Hui-Fang, Newman, Andrew J, Cheng, Soo-Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344849/ https://www.ncbi.nlm.nih.gov/pubmed/30395327 http://dx.doi.org/10.1093/nar/gky1089 |
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