Cargando…

Structural basis for acceptor RNA substrate selectivity of the 3′ terminal uridylyl transferase Tailor

Non-templated 3′-uridylation of RNAs has emerged as an important mechanism for regulating the processing, stability and biological function of eukaryotic transcripts. In Drosophila, oligouridine tailing by the terminal uridylyl transferase (TUTase) Tailor of numerous RNAs induces their degradation b...

Descripción completa

Detalles Bibliográficos
Autores principales: Kroupova, Alena, Ivaşcu, Anastasia, Reimão-Pinto, Madalena M, Ameres, Stefan L, Jinek, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344859/
https://www.ncbi.nlm.nih.gov/pubmed/30462292
http://dx.doi.org/10.1093/nar/gky1164

Ejemplares similares