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Exploring the effects of cosolutes and crowding on the volumetric and kinetic profile of the conformational dynamics of a poly dA loop DNA hairpin: a single-molecule FRET study

We investigated the volumetric and kinetic profile of the conformational landscape of a poly dA loop DNA hairpin (Hp) in the presence of salts, osmolytes and crowding media, mimicking the intracellular milieu, using single-molecule FRET methodology. Pressure modulation was applied to explore the vol...

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Detalles Bibliográficos
Autores principales:	Patra, Satyajit, Schuabb, Vitor, Kiesel, Irena, Knop, Jim-Marcel, Oliva, Rosario, Winter, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344865/ https://www.ncbi.nlm.nih.gov/pubmed/30418613 http://dx.doi.org/10.1093/nar/gky1122

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