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DNA mapping and kinetic modeling of the HrdB regulon in Streptomyces coelicolor

HrdB in streptomycetes is a principal sigma factor whose deletion is lethal. This is also the reason why its regulon has not been investigated so far. To overcome experimental obstacles, for investigating the HrdB regulon, we constructed a strain whose HrdB protein was tagged by an HA epitope. ChIP-...

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Detalles Bibliográficos
Autores principales:	Šmídová, Klára, Ziková, Alice, Pospíšil, Jiří, Schwarz, Marek, Bobek, Jan, Vohradsky, Jiri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344877/ https://www.ncbi.nlm.nih.gov/pubmed/30371884 http://dx.doi.org/10.1093/nar/gky1018

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