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The OTUD5–UBR5 complex regulates FACT-mediated transcription at damaged chromatin

Timely stalling and resumption of RNA polymerases at damaged chromatin are actively regulated processes. Prior work showed an importance of FACT histone chaperone in such process. Here we provide a new role of OTUD5 deubiquitinase in the FACT-dependent process. Through a DUB RNAi screen, we found OT...

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Detalles Bibliográficos
Autores principales:	de Vivo, Angelo, Sanchez, Anthony, Yegres, Jose, Kim, Jeonghyeon, Emly, Sylvia, Kee, Younghoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344881/ https://www.ncbi.nlm.nih.gov/pubmed/30508113 http://dx.doi.org/10.1093/nar/gky1219

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