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Retrograde BMP signaling activates neuronal gene expression through widespread deployment of a conserved BMP-responsive cis-regulatory activation element
Retrograde Bone Morphogenetic Protein (BMP) signaling in neurons is essential for the differentiation and synaptic function of many neuronal subtypes. BMP signaling regulates these processes via Smad transcription factor activity, yet the scope and nature of Smad-dependent gene regulation in neurons...
Autores principales: | Vuilleumier, Robin, Lian, Tianshun, Flibotte, Stephane, Khan, Zaynah N, Fuchs, Alisa, Pyrowolakis, George, Allan, Douglas W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344883/ https://www.ncbi.nlm.nih.gov/pubmed/30476189 http://dx.doi.org/10.1093/nar/gky1135 |
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