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Comprehensive catalog of dendritically localized mRNA isoforms from sub-cellular sequencing of single mouse neurons

BACKGROUND: RNA localization involves cis-motifs that are recognized by RNA-binding proteins (RBP), which then mediate localization to specific sub-cellular compartments. RNA localization is critical for many different cell functions, e.g., in neuronal dendrites, localization is a critical step for...

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Detalles Bibliográficos
Autores principales: Middleton, Sarah A., Eberwine, James, Kim, Junhyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344992/
https://www.ncbi.nlm.nih.gov/pubmed/30678683
http://dx.doi.org/10.1186/s12915-019-0630-z