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Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer
BACKGROUND: Limited understanding of the cancer biology of metastatic sites is a major factor contributing to poor outcomes in cancer patients. The regional lymph nodes are the most common site of metastasis in most solid cancers and their involvement is a strong predictor of relapse in breast cance...
Autores principales: | Ghaffari, Abdi, Hoskin, Victoria, Turashvili, Gulisa, Varma, Sonal, Mewburn, Jeff, Mullins, Graeme, Greer, Peter A., Kiefer, Friedemann, Day, Andrew G., Madarnas, Yolanda, SenGupta, Sandip, Elliott, Bruce E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345049/ https://www.ncbi.nlm.nih.gov/pubmed/30678714 http://dx.doi.org/10.1186/s13058-018-1079-7 |
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