ReDO_DB: the repurposing drugs in oncology database

Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-bas...

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Detalles Bibliográficos
Autores principales: Pantziarka, Pan, Verbaanderd, Ciska, Sukhatme, Vidula, Rica Capistrano, I, Crispino, Sergio, Gyawali, Bishal, Rooman, Ilse, Van Nuffel, An MT, Meheus, Lydie, Sukhatme, Vikas P, Bouche, Gauthier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345075/
https://www.ncbi.nlm.nih.gov/pubmed/30679953
http://dx.doi.org/10.3332/ecancer.2018.886
Descripción
Sumario:Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described. The database has been made available as an online open-access resource (http://www.redo-project.org/db/).

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