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Gamma-Secretase Inhibitor, DAPT, Prevents the Development of Retinopathy of Prematurity in a Rat Model by Regulating the Delta-Like Ligand 4/Notch Homolog-1 (DLL4/Notch-1) Pathway

BACKGROUND: Retinopathy of prematurity (ROP), or retrolental fibroplasia, affects premature infants who have undergone intensive care with oxygen therapy. This study aimed to investigate the inhibitory effect of the gamma-secretase inhibitor, DAPT, on neovascularization and its mechanism in a rat mo...

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Detalles Bibliográficos
Autores principales: Sun, Wei, Li, Jing, Li, Yinan, Zheng, Jiao, Zhang, Xiaoming, Huang, Xuelin, Li, Shujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345111/
https://www.ncbi.nlm.nih.gov/pubmed/30652694
http://dx.doi.org/10.12659/MSM.913828