Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity?

Age-associated hyper-inflammation or “inflamm-aging” has been linked to the development of chronic diseases and characterized as an unavoidable aspect of aging. However, the inflamm-aging model does not adequately address the potential anti-inflammatory effects of exercise training and the potential...

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Detalles Bibliográficos
Autores principales: Flynn, Michael G., Markofski, Melissa M., Carrillo, Andres E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345337/
https://www.ncbi.nlm.nih.gov/pubmed/30705775
http://dx.doi.org/10.14336/AD.2018.0326
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author Flynn, Michael G.
Markofski, Melissa M.
Carrillo, Andres E.
author_facet Flynn, Michael G.
Markofski, Melissa M.
Carrillo, Andres E.
author_sort Flynn, Michael G.
collection PubMed
description Age-associated hyper-inflammation or “inflamm-aging” has been linked to the development of chronic diseases and characterized as an unavoidable aspect of aging. However, the inflamm-aging model does not adequately address the potential anti-inflammatory effects of exercise training and the potential for exercise to ameliorate several age-related diseases. In this brief review, we introduce a new paradigm—inflamm-inactivity—that describes a potent counter-measure to age-associated inflammatory illness.
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spelling pubmed-63453372019-02-01 Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity? Flynn, Michael G. Markofski, Melissa M. Carrillo, Andres E. Aging Dis Review Age-associated hyper-inflammation or “inflamm-aging” has been linked to the development of chronic diseases and characterized as an unavoidable aspect of aging. However, the inflamm-aging model does not adequately address the potential anti-inflammatory effects of exercise training and the potential for exercise to ameliorate several age-related diseases. In this brief review, we introduce a new paradigm—inflamm-inactivity—that describes a potent counter-measure to age-associated inflammatory illness. JKL International LLC 2019-02-01 /pmc/articles/PMC6345337/ /pubmed/30705775 http://dx.doi.org/10.14336/AD.2018.0326 Text en Copyright: © 2019 Flynn et al. http://creativecommons.org/licenses/by/2.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Review
Flynn, Michael G.
Markofski, Melissa M.
Carrillo, Andres E.
Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity?
title Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity?
title_full Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity?
title_fullStr Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity?
title_full_unstemmed Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity?
title_short Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity?
title_sort elevated inflammatory status and increased risk of chronic disease in chronological aging: inflamm-aging or inflamm-inactivity?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345337/
https://www.ncbi.nlm.nih.gov/pubmed/30705775
http://dx.doi.org/10.14336/AD.2018.0326
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AT carrilloandrese elevatedinflammatorystatusandincreasedriskofchronicdiseaseinchronologicalaginginflammagingorinflamminactivity

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