Sex and Pubertal Differences in the Type 1 Interferon Pathway Associate With Both X Chromosome Number and Serum Sex Hormone Concentration

Type 1 interferons (IFN) are an antiviral cytokine family, important in juvenile onset systemic lupus erythematosus (jSLE) which is more common in females, around puberty. We report that plasmacytoid dendritic cells (pDC) from healthy females produced more type 1 IFN after toll like receptor (TLR) 7...

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Detalles Bibliográficos
Autores principales: Webb, Kate, Peckham, Hannah, Radziszewska, Anna, Menon, Madhvi, Oliveri, Paola, Simpson, Fraser, Deakin, Claire T., Lee, Sophie, Ciurtin, Coziana, Butler, Gary, Wedderburn, Lucy R., Ioannou, Yiannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345344/
https://www.ncbi.nlm.nih.gov/pubmed/30705679
http://dx.doi.org/10.3389/fimmu.2018.03167

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