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Genetic architecture of human thinness compared to severe obesity
The variation in weight within a shared environment is largely attributable to genetic factors. Whilst many genes/loci confer susceptibility to obesity, little is known about the genetic architecture of healthy thinness. Here, we characterise the heritability of thinness which we found was comparabl...
Autores principales: | Riveros-McKay, Fernando, Mistry, Vanisha, Bounds, Rebecca, Hendricks, Audrey, Keogh, Julia M., Thomas, Hannah, Henning, Elana, Corbin, Laura J., O’Rahilly, Stephen, Zeggini, Eleftheria, Wheeler, Eleanor, Barroso, Inês, Farooqi, I. Sadaf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345421/ https://www.ncbi.nlm.nih.gov/pubmed/30677029 http://dx.doi.org/10.1371/journal.pgen.1007603 |
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