Cargando…
Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease
The roles of retinoids in nonalcoholic fatty liver disease (NAFLD) remain unclear and a better understanding may lead to therapies that prevent or limit NAFLD progression. We examined the actions of retinoic acid receptor (RAR) agonists- AM80 for RARα and AC261066 for RARβ2- in a murine model of NAF...
Autores principales: | Melis, Marta, Tang, Xiao-Han, Trasino, Steven E., Patel, Viral M., Stummer, Daniel J., Jessurun, Jose, Gudas, Lorraine J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345457/ https://www.ncbi.nlm.nih.gov/pubmed/30677086 http://dx.doi.org/10.1371/journal.pone.0211071 |
Ejemplares similares
-
Obesity Leads to Tissue, but not Serum Vitamin A Deficiency
por: Trasino, Steven E., et al.
Publicado: (2015) -
Retinoids in the Pathogenesis and Treatment of Liver Diseases
por: Melis, Marta, et al.
Publicado: (2022) -
Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease
por: Tang, Xiao-Han, et al.
Publicado: (2021) -
Retinoic Acid Receptor β Loss in Hepatocytes Increases Steatosis and Elevates the Integrated Stress Response in Alcohol-Associated Liver Disease
por: Melis, Marta, et al.
Publicado: (2023) -
A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease
por: Tang, Xiao-Han, et al.
Publicado: (2021)