Cargando…

Resolving the apparent transmission paradox of African sleeping sickness

Human African trypanosomiasis (HAT), or African sleeping sickness, is a fatal disease found throughout sub-Saharan Africa. The disease is close to elimination in many areas, although it was similarly close to elimination once before and subsequently reemerged, despite seemingly low rates of transmis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Capewell, Paul, Atkins, Katie, Weir, William, Jamonneau, Vincent, Camara, Mamadou, Clucas, Caroline, Swar, Nono-Raymond K., Ngoyi, Dieudonne M., Rotureau, Brice, Garside, Paul, Galvani, Alison P., Bucheton, Bruno, MacLeod, Annette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Essay
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345479/ https://www.ncbi.nlm.nih.gov/pubmed/30633739 http://dx.doi.org/10.1371/journal.pbio.3000105

Ejemplares similares

The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes
por: Capewell, Paul, et al.
Publicado: (2016)

Extravascular Dermal Trypanosomes in Suspected and Confirmed Cases of gambiense Human African Trypanosomiasis
por: Camara, Mariame, et al.
Publicado: (2020)

Population genomics reveals the origin and asexual evolution of human infective trypanosomes
por: Weir, William, et al.
Publicado: (2016)

Sleeping sickness in the historical focus of forested Guinea: update using a geographically based method
por: Courtin, Fabrice, et al.
Publicado: (2019)

Evaluating long-term effectiveness of sleeping sickness control measures in Guinea
por: Pandey, Abhishek, et al.
Publicado: (2015)

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis
por: Cooper, Anneli, et al.
Publicado: (2017)

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection
por: Sinton, Matthew C., et al.
Publicado: (2023)

Human host determinants influencing the outcome of Trypanosoma brucei gambiense infections
por: Bucheton, B, et al.
Publicado: (2011)

SNPs in IL4 and IFNG show no protective associations with human African trypanosomiasis in the Democratic Republic of the Congo: a case-control study
por: Fataki Asina, Olivier, et al.
Publicado: (2020)

A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome
por: CAPEWELL, PAUL, et al.
Publicado: (2015)

Epidemiology of Sleeping Sickness in Boffa (Guinea): Where Are the Trypanosomes?
por: Kagbadouno, Moise Saa, et al.
Publicado: (2012)

A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense
por: Cooper, Anneli, et al.
Publicado: (2016)

Revisiting the Immune Trypanolysis Test to Optimise Epidemiological Surveillance and Control of Sleeping Sickness in West Africa
por: Jamonneau, Vincent, et al.
Publicado: (2010)

Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination?
por: Büscher, Philippe, et al.
Publicado: (2018)

Reducing Human-Tsetse Contact Significantly Enhances the Efficacy of Sleeping Sickness Active Screening Campaigns: A Promising Result in the Context of Elimination
por: Courtin, Fabrice, et al.
Publicado: (2015)

Improved Models of Mini Anion Exchange Centrifugation Technique (mAECT) and Modified Single Centrifugation (MSC) for Sleeping Sickness Diagnosis and Staging
por: Büscher, Philippe, et al.
Publicado: (2009)

γδ T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection
por: Quintana, Juan F., et al.
Publicado: (2023)

Unravelling Human Trypanotolerance: IL8 is Associated with Infection Control whereas IL10 and TNFα Are Associated with Subsequent Disease Development
por: Ilboudo, Hamidou, et al.
Publicado: (2014)

Accelerating elimination of sleeping sickness from the Guinean littoral through enhanced screening in the post-Ebola context: A retrospective analysis
por: Camara, Oumou, et al.
Publicado: (2021)

The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense
por: Capewell, Paul, et al.
Publicado: (2013)

Population Genetics and Reproductive Strategies of African Trypanosomes: Revisiting Available Published Data
por: Koffi, Mathurin, et al.
Publicado: (2015)

Accuracy of Individual Rapid Tests for Serodiagnosis of Gambiense Sleeping Sickness in West Africa
por: Jamonneau, Vincent, et al.
Publicado: (2015)

Tsetse Control and the Elimination of Gambian Sleeping Sickness
por: Lehane, Mike, et al.
Publicado: (2016)

Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea
por: Kaboré, Justin Windingoudi, et al.
Publicado: (2017)

Correction: The miRNA and mRNA Signatures of Peripheral Blood Cells in Humans Infected with Trypanosoma brucei gambiense
por: Lueong, Smiths, et al.
Publicado: (2013)

The miRNA and mRNA Signatures of Peripheral Blood Cells in Humans Infected with Trypanosoma brucei gambiense
por: Leong, Smiths, et al.
Publicado: (2013)

Symptoms and exacerbations in asthma: an apparent paradox?
por: Morjaria, Jaymin B., et al.
Publicado: (2019)

Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis
por: Ilboudo, Hamidou, et al.
Publicado: (2017)

High Levels of Genetic Diversity within Nilo-Saharan Populations: Implications for Human Adaptation
por: Mulindwa, Julius, et al.
Publicado: (2020)

Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis
por: Girard, Alexandre, et al.
Publicado: (2021)

Cerebrospinal Fluid-Derived Microvesicles From Sleeping Sickness Patients Alter Protein Expression in Human Astrocytes
por: Dozio, Vito, et al.
Publicado: (2019)

Prevalence of blood and skin trypanosomes in domestic and wild fauna from two sleeping sickness foci in Southern Cameroon
por: Magang, Eugenie Melaine Kemta, et al.
Publicado: (2023)

A targeted door-to-door strategy for sleeping sickness detection in low-prevalence settings in Côte d’Ivoire
por: Koffi, Mathurin, et al.
Publicado: (2016)

The separation of trypanosomes from blood by anion exchange chromatography: From Sheila Lanham’s discovery 50 years ago to a gold standard for sleeping sickness diagnosis
por: Lejon, Veerle, et al.
Publicado: (2019)

To the Skin and Beyond: The Immune Response to African Trypanosomes as They Enter and Exit the Vertebrate Host
por: Alfituri, Omar A., et al.
Publicado: (2020)

Corrigendum: To the Skin and Beyond: The Immune Response to African Trypanosomes as They Enter and Exit the Vertebrate Host
por: Alfituri, Omar A., et al.
Publicado: (2021)

Enhancing research integration to improve One Health actions: learning lessons from neglected tropical diseases experiences
por: Rotureau, Brice, et al.
Publicado: (2022)

Immune trypanolysis test as a promising bioassay to monitor the elimination of gambiense human African trypanosomiasis
por: Dama, Emilie, et al.
Publicado: (2019)

Isolation of Trypanosoma brucei gambiense from Cured and Relapsed Sleeping Sickness Patients and Adaptation to Laboratory Mice
por: Pyana, Patient Pati, et al.
Publicado: (2011)

Specificity of malaria rapid diagnostic tests is affected by Trypanosoma brucei gambiense sleeping sickness
por: Gillet, Philippe, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_20v1p5qiqut457q3lgglovu4r6