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The Genomic Footprints of the Fall and Recovery of the Crested Ibis

Human-induced environmental change and habitat fragmentation pose major threats to biodiversity and require active conservation efforts to mitigate their consequences. Genetic rescue through translocation and the introduction of variation into imperiled populations has been argued as a powerful mean...

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Autores principales: Feng, Shaohong, Fang, Qi, Barnett, Ross, Li, Cai, Han, Sojung, Kuhlwilm, Martin, Zhou, Long, Pan, Hailin, Deng, Yuan, Chen, Guangji, Gamauf, Anita, Woog, Friederike, Prys-Jones, Robert, Marques-Bonet, Tomas, Gilbert, M. Thomas P., Zhang, Guojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345625/
https://www.ncbi.nlm.nih.gov/pubmed/30639104
http://dx.doi.org/10.1016/j.cub.2018.12.008
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author Feng, Shaohong
Fang, Qi
Barnett, Ross
Li, Cai
Han, Sojung
Kuhlwilm, Martin
Zhou, Long
Pan, Hailin
Deng, Yuan
Chen, Guangji
Gamauf, Anita
Woog, Friederike
Prys-Jones, Robert
Marques-Bonet, Tomas
Gilbert, M. Thomas P.
Zhang, Guojie
author_facet Feng, Shaohong
Fang, Qi
Barnett, Ross
Li, Cai
Han, Sojung
Kuhlwilm, Martin
Zhou, Long
Pan, Hailin
Deng, Yuan
Chen, Guangji
Gamauf, Anita
Woog, Friederike
Prys-Jones, Robert
Marques-Bonet, Tomas
Gilbert, M. Thomas P.
Zhang, Guojie
author_sort Feng, Shaohong
collection PubMed
description Human-induced environmental change and habitat fragmentation pose major threats to biodiversity and require active conservation efforts to mitigate their consequences. Genetic rescue through translocation and the introduction of variation into imperiled populations has been argued as a powerful means to preserve, or even increase, the genetic diversity and evolutionary potential of endangered species [1, 2, 3, 4]. However, factors such as outbreeding depression [5, 6] and a reduction in available genetic diversity render the success of such approaches uncertain. An improved evaluation of the consequence of genetic restoration requires knowledge of temporal changes to genetic diversity before and after the advent of management programs. To provide such information, a growing number of studies have included small numbers of genomic loci extracted from historic and even ancient specimens [7, 8]. We extend this approach to its natural conclusion, by characterizing the complete genomic sequences of modern and historic population samples of the crested ibis (Nipponia nippon), an endangered bird that is perhaps the most successful example of how conservation effort has brought a species back from the brink of extinction. Though its once tiny population has today recovered to >2,000 individuals [9], this process was accompanied by almost half of ancestral loss of genetic variation and high deleterious mutation load. We furthermore show how genetic drift coupled to inbreeding following the population bottleneck has largely purged the ancient polymorphisms from the current population. In conclusion, we demonstrate the unique promise of exploiting genomic information held within museum samples for conservation and ecological research.
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spelling pubmed-63456252019-01-28 The Genomic Footprints of the Fall and Recovery of the Crested Ibis Feng, Shaohong Fang, Qi Barnett, Ross Li, Cai Han, Sojung Kuhlwilm, Martin Zhou, Long Pan, Hailin Deng, Yuan Chen, Guangji Gamauf, Anita Woog, Friederike Prys-Jones, Robert Marques-Bonet, Tomas Gilbert, M. Thomas P. Zhang, Guojie Curr Biol Article Human-induced environmental change and habitat fragmentation pose major threats to biodiversity and require active conservation efforts to mitigate their consequences. Genetic rescue through translocation and the introduction of variation into imperiled populations has been argued as a powerful means to preserve, or even increase, the genetic diversity and evolutionary potential of endangered species [1, 2, 3, 4]. However, factors such as outbreeding depression [5, 6] and a reduction in available genetic diversity render the success of such approaches uncertain. An improved evaluation of the consequence of genetic restoration requires knowledge of temporal changes to genetic diversity before and after the advent of management programs. To provide such information, a growing number of studies have included small numbers of genomic loci extracted from historic and even ancient specimens [7, 8]. We extend this approach to its natural conclusion, by characterizing the complete genomic sequences of modern and historic population samples of the crested ibis (Nipponia nippon), an endangered bird that is perhaps the most successful example of how conservation effort has brought a species back from the brink of extinction. Though its once tiny population has today recovered to >2,000 individuals [9], this process was accompanied by almost half of ancestral loss of genetic variation and high deleterious mutation load. We furthermore show how genetic drift coupled to inbreeding following the population bottleneck has largely purged the ancient polymorphisms from the current population. In conclusion, we demonstrate the unique promise of exploiting genomic information held within museum samples for conservation and ecological research. Cell Press 2019-01-21 /pmc/articles/PMC6345625/ /pubmed/30639104 http://dx.doi.org/10.1016/j.cub.2018.12.008 Text en © 2018 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Feng, Shaohong
Fang, Qi
Barnett, Ross
Li, Cai
Han, Sojung
Kuhlwilm, Martin
Zhou, Long
Pan, Hailin
Deng, Yuan
Chen, Guangji
Gamauf, Anita
Woog, Friederike
Prys-Jones, Robert
Marques-Bonet, Tomas
Gilbert, M. Thomas P.
Zhang, Guojie
The Genomic Footprints of the Fall and Recovery of the Crested Ibis
title The Genomic Footprints of the Fall and Recovery of the Crested Ibis
title_full The Genomic Footprints of the Fall and Recovery of the Crested Ibis
title_fullStr The Genomic Footprints of the Fall and Recovery of the Crested Ibis
title_full_unstemmed The Genomic Footprints of the Fall and Recovery of the Crested Ibis
title_short The Genomic Footprints of the Fall and Recovery of the Crested Ibis
title_sort genomic footprints of the fall and recovery of the crested ibis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345625/
https://www.ncbi.nlm.nih.gov/pubmed/30639104
http://dx.doi.org/10.1016/j.cub.2018.12.008
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