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The Transcriptional Control of Iron Homeostasis in Plants: A Tale of bHLH Transcription Factors?

Iron is one of the most important micronutrients in plants as it is involved in many cellular functions (e.g., photosynthesis and respiration). Any defect in iron availability will affect plant growth and development as well as crop yield and plant product quality. Thus, iron homeostasis must be tig...

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Autores principales: Gao, Fei, Robe, Kevin, Gaymard, Frederic, Izquierdo, Esther, Dubos, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345679/
https://www.ncbi.nlm.nih.gov/pubmed/30713541
http://dx.doi.org/10.3389/fpls.2019.00006
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author Gao, Fei
Robe, Kevin
Gaymard, Frederic
Izquierdo, Esther
Dubos, Christian
author_facet Gao, Fei
Robe, Kevin
Gaymard, Frederic
Izquierdo, Esther
Dubos, Christian
author_sort Gao, Fei
collection PubMed
description Iron is one of the most important micronutrients in plants as it is involved in many cellular functions (e.g., photosynthesis and respiration). Any defect in iron availability will affect plant growth and development as well as crop yield and plant product quality. Thus, iron homeostasis must be tightly controlled in order to ensure optimal absorption of this mineral element. Understanding mechanisms governing iron homeostasis in plants has been the focus of several studies during the past 10 years. These studies have greatly improved our understanding of the mechanisms involved, revealing a sophisticated iron-dependent transcriptional regulatory network. Strikingly, these studies have also highlighted that this regulatory web relies on the activity of numerous transcriptional regulators that belong to the same group of transcription factors (TF), the bHLH (basic helix-loop-helix) family. This is best exemplified in Arabidopsis where, to date, 16 bHLH TF have been characterized as involved in this process and acting in a complex regulatory cascade. Interestingly, among these bHLH TF some form specific clades, indicating that peculiar function dedicated to the maintenance of iron homeostasis, have emerged during the course of the evolution of the green lineage. Within this mini review, we present new insights on the control of iron homeostasis and the involvement of bHLH TF in this metabolic process.
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spelling pubmed-63456792019-02-01 The Transcriptional Control of Iron Homeostasis in Plants: A Tale of bHLH Transcription Factors? Gao, Fei Robe, Kevin Gaymard, Frederic Izquierdo, Esther Dubos, Christian Front Plant Sci Plant Science Iron is one of the most important micronutrients in plants as it is involved in many cellular functions (e.g., photosynthesis and respiration). Any defect in iron availability will affect plant growth and development as well as crop yield and plant product quality. Thus, iron homeostasis must be tightly controlled in order to ensure optimal absorption of this mineral element. Understanding mechanisms governing iron homeostasis in plants has been the focus of several studies during the past 10 years. These studies have greatly improved our understanding of the mechanisms involved, revealing a sophisticated iron-dependent transcriptional regulatory network. Strikingly, these studies have also highlighted that this regulatory web relies on the activity of numerous transcriptional regulators that belong to the same group of transcription factors (TF), the bHLH (basic helix-loop-helix) family. This is best exemplified in Arabidopsis where, to date, 16 bHLH TF have been characterized as involved in this process and acting in a complex regulatory cascade. Interestingly, among these bHLH TF some form specific clades, indicating that peculiar function dedicated to the maintenance of iron homeostasis, have emerged during the course of the evolution of the green lineage. Within this mini review, we present new insights on the control of iron homeostasis and the involvement of bHLH TF in this metabolic process. Frontiers Media S.A. 2019-01-18 /pmc/articles/PMC6345679/ /pubmed/30713541 http://dx.doi.org/10.3389/fpls.2019.00006 Text en Copyright © 2019 Gao, Robe, Gaymard, Izquierdo and Dubos. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Gao, Fei
Robe, Kevin
Gaymard, Frederic
Izquierdo, Esther
Dubos, Christian
The Transcriptional Control of Iron Homeostasis in Plants: A Tale of bHLH Transcription Factors?
title The Transcriptional Control of Iron Homeostasis in Plants: A Tale of bHLH Transcription Factors?
title_full The Transcriptional Control of Iron Homeostasis in Plants: A Tale of bHLH Transcription Factors?
title_fullStr The Transcriptional Control of Iron Homeostasis in Plants: A Tale of bHLH Transcription Factors?
title_full_unstemmed The Transcriptional Control of Iron Homeostasis in Plants: A Tale of bHLH Transcription Factors?
title_short The Transcriptional Control of Iron Homeostasis in Plants: A Tale of bHLH Transcription Factors?
title_sort transcriptional control of iron homeostasis in plants: a tale of bhlh transcription factors?
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345679/
https://www.ncbi.nlm.nih.gov/pubmed/30713541
http://dx.doi.org/10.3389/fpls.2019.00006
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