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Activin Receptor Ligand Blocking and Cancer Have Distinct Effects on Protein and Redox Homeostasis in Skeletal Muscle and Liver

Muscle wasting in cancer cachexia can be alleviated by blocking activin receptor type 2 (ACVR2) ligands through changes in protein synthesis/degradation. These changes in cellular and protein metabolism may alter protein homeostasis. First, we elucidated the acute (1–2 days) and 2-week effects of bl...

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Detalles Bibliográficos
Autores principales:	Hentilä, Jaakko, Nissinen, Tuuli A., Korkmaz, Ayhan, Lensu, Sanna, Silvennoinen, Mika, Pasternack, Arja, Ritvos, Olli, Atalay, Mustafa, Hulmi, Juha J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345696/ https://www.ncbi.nlm.nih.gov/pubmed/30713500 http://dx.doi.org/10.3389/fphys.2018.01917

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