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Characterization of drug binding within the HCN1 channel pore

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels mediate rhythmic electrical activity of cardiac pacemaker cells, and in neurons play important roles in setting resting membrane potentials, dendritic integration, neuronal pacemaking, and establishing action potential threshold. Blo...

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Detalles Bibliográficos
Autores principales:	Tanguay, Jérémie, Callahan, Karen M., D’Avanzo, Nazzareno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345760/ https://www.ncbi.nlm.nih.gov/pubmed/30679654 http://dx.doi.org/10.1038/s41598-018-37116-2

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