Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function

Albuminuria affects millions of people, and is an independent risk factor for kidney failure, cardiovascular morbidity and death. The key cell that prevents albuminuria is the terminally differentiated glomerular podocyte. Here we report the evolutionary importance of the enzyme Glycogen Synthase Ki...

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Detalles Bibliográficos
Autores principales: Hurcombe, J. A., Hartley, P., Lay, A. C., Ni, L., Bedford, J. J., Leader, J. P., Singh, S., Murphy, A., Scudamore, C. L., Marquez, E., Barrington, A. F., Pinto, V., Marchetti, M., Wong, L.-F., Uney, J., Saleem, M. A., Mathieson, P. W., Patel, S., Walker, R. J., Woodgett, J. R., Quaggin, S. E., Welsh, G. I., Coward, R. J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345761/
https://www.ncbi.nlm.nih.gov/pubmed/30679422
http://dx.doi.org/10.1038/s41467-018-08235-1

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