STAT3 is activated in multicellular spheroids of colon carcinoma cells and mediates expression of IRF9 and interferon stimulated genes

Three-dimensional cell cultures, such as multicellular spheroids (MCS), reflect the in vivo architecture of solid tumours and multicellular drug resistance. We previously identified interferon regulatory factor 9 (IRF9) to be responsible for the up-regulation of a subset of interferon (IFN)-stimulat...

Descripción completa

Detalles Bibliográficos
Autores principales: Edsbäcker, Elin, Serviss, Jason T., Kolosenko, Iryna, Palm-Apergi, Caroline, De Milito, Angelo, Tamm, Katja Pokrovskaja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345781/
https://www.ncbi.nlm.nih.gov/pubmed/30679726
http://dx.doi.org/10.1038/s41598-018-37294-z

Ejemplares similares

Ejemplares similares