Upregulated long noncoding RNA LOC105375913 induces tubulointerstitial fibrosis in focal segmental glomerulosclerosis

Tubulointerstitial fibrosis impacts renal prognosis of focal segmental glomerulosclerosis (FSGS). Based on transcriptomic analysis, we found that the level of LOC105375913 was increased in tubular cells of FSGS patients. C3a induced the expression of LOC105375913, which promoted the expression of fi...

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Detalles Bibliográficos
Autores principales: Han, Runhong, Hu, Shuai, Qin, Weisong, Shi, Jingsong, Zeng, Caihong, Bao, Hao, Liu, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345783/
https://www.ncbi.nlm.nih.gov/pubmed/30679767
http://dx.doi.org/10.1038/s41598-018-36902-2

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