Cargando…

The Impact of Cardiac Lipotoxicity on Cardiac Function and Mirnas Signature in Obese and Non-Obese Rats with Myocardial Infarction

Cardiac lipotoxicity is involved in the cardiac functional consequences associated with obesity. Therefore, the aim of this study was to explore whether changes in the mitochondrial lipid cardiac profile could reflect differences in cardiac function and structure in obese and non-obese rats with myo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marín-Royo, Gema, Ortega-Hernández, Adriana, Martínez-Martínez, Ernesto, Jurado-López, Raquel, Luaces, María, Islas, Fabián, Gómez-Garre, Dulcenombre, Delgado-Valero, Beatriz, Lagunas, Esther, Ramchandani, Bunty, García-Bouza, Mónica, Nieto, María Luisa, Cachofeiro, Victoria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345821/ https://www.ncbi.nlm.nih.gov/pubmed/30679580 http://dx.doi.org/10.1038/s41598-018-36914-y

Ejemplares similares

The Crosstalk between Cardiac Lipotoxicity and Mitochondrial Oxidative Stress in the Cardiac Alterations in Diet-Induced Obesity in Rats
por: Jiménez-González, Sara, et al.
Publicado: (2020)

Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity
por: Marín-Royo, Gema, et al.
Publicado: (2018)

Mitochondrial Oxidative Stress Promotes Cardiac Remodeling in Myocardial Infarction through the Activation of Endoplasmic Reticulum Stress
por: Souza-Neto, Francisco V., et al.
Publicado: (2022)

The role of oxidative stress in the crosstalk between leptin and mineralocorticoid receptor in the cardiac fibrosis associated with obesity
por: Gutiérrez-Tenorio, Josué, et al.
Publicado: (2017)

The Interaction between Mitochondrial Oxidative Stress and Gut Microbiota in the Cardiometabolic Consequences in Diet-Induced Obese Rats
por: Ortega-Hernández, Adriana, et al.
Publicado: (2020)

Mitochondrial Oxidative Stress Induces Cardiac Fibrosis in Obese Rats through Modulation of Transthyretin
por: Martínez-Martínez, Ernesto, et al.
Publicado: (2022)

Importance of cardiac imaging assessment of epicardial adipose tissue after a first episode of myocardial infarction
por: Islas, Fabián, et al.
Publicado: (2022)

Oxidative Stress in Obesity
por: Martínez-Martínez, Ernesto, et al.
Publicado: (2022)

The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats
por: Miana, María, et al.
Publicado: (2015)

The Interplay of Mitochondrial Oxidative Stress and Endoplasmic Reticulum Stress in Cardiovascular Fibrosis in Obese Rats
por: Souza-Neto, Francisco V., et al.
Publicado: (2021)

A Role for Soluble ST2 in Vascular Remodeling Associated with Obesity in Rats
por: Martínez-Martínez, Ernesto, et al.
Publicado: (2013)

DIOL Triterpenes Block Profibrotic Effects of Angiotensin II and Protect from Cardiac Hypertrophy
por: Martín, Ruben, et al.
Publicado: (2012)

Oxidative Stress and Vascular Damage in the Context of Obesity: The Hidden Guest
por: Martínez-Martínez, Ernesto, et al.
Publicado: (2021)

Linking phospholipid homeostasis with cardiac lipotoxicity in flies
Publicado: (2011)

Identification of a Plasma Microrna Signature as Biomarker of Subaneurysmal Aortic Dilation in Patients with High Cardiovascular Risk
por: Torres-Do Rego, Ana, et al.
Publicado: (2020)

Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring
por: Jarvie, Eleanor, et al.
Publicado: (2010)

Quantification of epicardial adipose tissue in morbidly obese patients before and after bariatric surgery
por: Luaces, María, et al.
Publicado: (2014)

Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities
por: Opazo-Ríos, Lucas, et al.
Publicado: (2020)

Lipotoxicity and β Cell Maintenance in Obesity and Type 2 Diabetes
por: Ye, Risheng, et al.
Publicado: (2019)

Analysis of probable lipotoxic damage and myocardial fibrosis in epicardial obesity
por: Chumakova, Galina, et al.
Publicado: (2021)

Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila
por: Guida, Maria Clara, et al.
Publicado: (2019)

Fibrosis, the Bad Actor in Cardiorenal Syndromes: Mechanisms Involved
por: Delgado-Valero, Beatriz, et al.
Publicado: (2021)

Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox
por: Khatua, Biswajit, et al.
Publicado: (2021)

Fatty old hearts: role of cardiac lipotoxicity in age-related cardiomyopathy
por: Drosatos, Konstantinos
Publicado: (2016)

Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels
por: Lucas, Elisa, et al.
Publicado: (2016)

CCN5 knockout mice exhibit lipotoxic cardiomyopathy with mild obesity and diabetes
por: Kim, Jihwa, et al.
Publicado: (2018)

Hepatic Choline Transport Is Inhibited During Fatty Acid–Induced Lipotoxicity and Obesity
por: O’Dwyer, Conor, et al.
Publicado: (2020)

Dehydrozingerone inhibits renal lipotoxicity in high‐fat diet–induced obese mice
por: Lee, Eun Soo, et al.
Publicado: (2021)

Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity
por: Zhang, Yudi, et al.
Publicado: (2021)

Notoginsenoside R1 Ameliorates Cardiac Lipotoxicity Through AMPK Signaling Pathway
por: Tian, Xue, et al.
Publicado: (2022)

The Role of Gender Differences and Menopause in Obesity-Related Renal Disease, Renal Inflammation and Lipotoxicity
por: Afonso-Alí, Aaron, et al.
Publicado: (2023)

Interconnection between Cardiac Cachexia and Heart Failure—Protective Role of Cardiac Obesity
por: Soto, María Elena, et al.
Publicado: (2022)

Cardiac Obesity and Cardiac Cachexia: Is There a Pathophysiological Link?
por: Selthofer-Relatić, K., et al.
Publicado: (2019)

Differential Effects of Cardiac Rehabilitation in Obese and Non-Obese Population
por: Atti, Varunsiri, et al.
Publicado: (2021)

Systemic and heart autonomous effects of sphingosine Δ4 desaturase deficiency in lipotoxic cardiac pathophysiology
por: Walls, Stanley M., et al.
Publicado: (2020)

Renal Lipotoxicity-Associated Inflammation and Insulin Resistance Affects Actin Cytoskeleton Organization in Podocytes
por: Martínez-García, Cristina, et al.
Publicado: (2015)

Cardiac Autonomic Functions in Obese Children
por: Taşçılar, Mehmet Emre, et al.
Publicado: (2011)

Cardiac and Metabolic Variables in Obese Dogs
por: Tropf, M., et al.
Publicado: (2017)

Secreted Phospholipase A(2)-IIA Modulates Transdifferentiation of Cardiac Fibroblast through EGFR Transactivation: An Inflammation–Fibrosis Link
por: Martin, Ruben, et al.
Publicado: (2020)

Treatment with didemnin B, an elongation factor 1A inhibitor, improves hepatic lipotoxicity in obese mice
por: Hetherington, Alexandra M., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1bkjkscbg2h07sahtcnfqc9kqf