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Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system
IgG is an indispensable biological experimental tool as well as a widely-used therapeutic protein. However, cell culture-based expression of monoclonal IgG is costly and time-consuming, making this process difficult to use for high-throughput screening in early-stage evaluation of biologics. With th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345822/ https://www.ncbi.nlm.nih.gov/pubmed/30679500 http://dx.doi.org/10.1038/s41598-018-36691-8 |