Ascorbic acid encapsulated into negatively charged liposomes exhibits increased skin permeation, retention and enhances collagen synthesis by fibroblasts

Ascorbic acid (AA) is widely used in cosmetic formulations due to its antioxidant property and ability to increase collagen synthesis. Here, we encapsulated AA in vesicles with different lipid compositions. Negative liposome charge favored AA skin retention, with accumulation of 37 ± 12 and 74 ± 23 ...

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Detalles Bibliográficos
Autores principales: Maione-Silva, Lorena, de Castro, Elisandra Gava, Nascimento, Thais Leite, Cintra, Emílio Ramos, Moreira, Larissa Cleres, Cintra, Bertilha Alves Santana, Valadares, Marize Campos, Lima, Eliana Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345870/
https://www.ncbi.nlm.nih.gov/pubmed/30679479
http://dx.doi.org/10.1038/s41598-018-36682-9

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