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Targeting the insulin-like growth factor-1 receptor in MTAP-deficient renal cell carcinoma
Renal cell carcinoma (RCC) has emerged as a metabolic disease characterized by dysregulated expression of metabolic enzymes. Patients with metastatic RCC have an unusually poor prognosis and near-universal resistance to all current therapies. To improve RCC treatment and the survival rate of patient...
Autores principales: | Xu, Jihao, Chang, Wen-Hsin, Fong, Lon Wolf R., Weiss, Robert H., Yu, Sung-Liang, Chen, Ching-Hsien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345872/ https://www.ncbi.nlm.nih.gov/pubmed/30701095 http://dx.doi.org/10.1038/s41392-019-0035-z |
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