Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer

DNA replication timing is known to facilitate the establishment of the epigenome, however, the intimate connection between replication timing and changes to the genome and epigenome in cancer remain largely uncharacterised. Here, we perform Repli-Seq and integrated epigenome analyses and demonstrate...

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Detalles Bibliográficos
Autores principales: Du, Qian, Bert, Saul A., Armstrong, Nicola J., Caldon, C. Elizabeth, Song, Jenny Z., Nair, Shalima S., Gould, Cathryn M., Luu, Phuc-Loi, Peters, Timothy, Khoury, Amanda, Qu, Wenjia, Zotenko, Elena, Stirzaker, Clare, Clark, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345877/
https://www.ncbi.nlm.nih.gov/pubmed/30679435
http://dx.doi.org/10.1038/s41467-019-08302-1

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