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Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes
Ceramides are sphingolipids with defined acyl chain lengths, which are produced by corresponding ceramide synthases (CerS1-6). In experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), the ablation of CerS2 suppresses EAE-pathology by reducing neutrophil migrati...
Autores principales: | Kurz, Jennifer, Barthelmes, Julia, Blum, Leonard, Ulshöfer, Thomas, Wegner, Marthe-Susanna, Ferreirós, Nerea, Roser, Luise, Geisslinger, Gerd, Grösch, Sabine, Schiffmann, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345911/ https://www.ncbi.nlm.nih.gov/pubmed/30679689 http://dx.doi.org/10.1038/s41598-018-37342-8 |
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