Phenotypic analysis of Myo10 knockout (Myo10(tm2/tm2)) mice lacking full-length (motorized) but not brain-specific headless myosin X

We investigated the physiological functions of Myo10 (myosin X) using Myo10 reporter knockout (Myo10(tm2)) mice. Full-length (motorized) Myo10 protein was deleted, but the brain-specific headless (Hdl) isoform (Hdl-Myo10) was still expressed in homozygous mutants. In vitro, we confirmed that Hdl-Myo...

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Detalles Bibliográficos
Autores principales: Bachg, Anne C., Horsthemke, Markus, Skryabin, Boris V., Klasen, Tim, Nagelmann, Nina, Faber, Cornelius, Woodham, Emma, Machesky, Laura M., Bachg, Sandra, Stange, Richard, Jeong, Hyun-Woo, Adams, Ralf H., Bähler, Martin, Hanley, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345916/
https://www.ncbi.nlm.nih.gov/pubmed/30679680
http://dx.doi.org/10.1038/s41598-018-37160-y

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