Cargando…

A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation

Understanding HIV remission in rare individuals who initiated antiretroviral therapy (ART) soon after infection and then discontinued, may inform HIV cure interventions. Here we describe features of virus and host of a perinatally HIV-1 infected child with long-term sustained virological control. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Violari, Avy, Cotton, Mark F., Kuhn, Louise, Schramm, Diana B., Paximadis, Maria, Loubser, Shayne, Shalekoff, Sharon, Da Costa Dias, Bianca, Otwombe, Kennedy, Liberty, Afaaf, McIntyre, James, Babiker, Abdel, Gibb, Diana, Tiemessen, Caroline T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345921/ https://www.ncbi.nlm.nih.gov/pubmed/30679439 http://dx.doi.org/10.1038/s41467-019-08311-0

Ejemplares similares

Impact of Disclosure over Time on the Emotional Well-Being of Children with Perinatally Acquired HIV Infection in South Africa
por: Buckley, Janice, et al.
Publicado: (2022)

Human leukocyte antigen class I (A, B and C) allele and haplotype variation in a South African Mixed ancestry population
por: Loubser, Shayne, et al.
Publicado: (2017)

A retrospective case-cohort study comparing treatment outcomes in abacavir versus stavudine containing first line antiretroviral treatment regimens in children <3yrs old, at a paediatric programme based in Soweto, South Africa
por: Cassim, Haseena, et al.
Publicado: (2017)

Five year neurodevelopment outcomes of perinatally HIV‐infected children on early limited or deferred continuous antiretroviral therapy
por: Laughton, Barbara, et al.
Publicado: (2018)

Early severe HIV disease precedes early antiretroviral therapy in infants: Are we too late?
por: Innes, Steve, et al.
Publicado: (2014)

Children's Positive and Negative Emotional Responses to an HIV Disclosure Study in South Africa
por: Ramsammy, Candice W., et al.
Publicado: (2022)

Experiences of South African caregivers disclosing to their children living with HIV: Qualitative investigations
por: Joyce, Celeste, et al.
Publicado: (2022)

Thymic Output and CD4 T-Cell Reconstitution in HIV-Infected Children on Early and Interrupted Antiretroviral Treatment: Evidence from the Children with HIV Early Antiretroviral Therapy Trial
por: Lewis, Joanna, et al.
Publicado: (2017)

Distinct epigenetic profiles in children with perinatally-acquired HIV on antiretroviral therapy
por: Shiau, Stephanie, et al.
Publicado: (2019)

Does early initiation of ART in infants affect virological and resistance outcomes? Data from the CHER trial after 6 years of follow-up
por: Violari, A, et al.
Publicado: (2012)

Normalization of B Cell Subsets but Not T Follicular Helper Phenotypes in Infants With Very Early Antiretroviral Treatment
por: Shalekoff, Sharon, et al.
Publicado: (2021)

Early ART-initiation and longer ART duration reduces HIV-1 proviral DNA levels in children from the CHER trial
por: Payne, Helen, et al.
Publicado: (2021)

Age at antiretroviral therapy initiation and cell-associated HIV-1 DNA levels in HIV-1-infected children
por: Kuhn, Louise, et al.
Publicado: (2018)

Naive B Cell Output in HIV-Infected and HIV-Uninfected Children
por: Payne, Helen, et al.
Publicado: (2019)

Influence of intragenic CCL3 haplotypes and CCL3L copy number in HIV-1 infection in a sub-Saharan African population
por: Paximadis, Maria, et al.
Publicado: (2012)

Utility of clinical parameters to identify HIV infection in infants below ten weeks of age in South Africa: a prospective cohort study
por: Jaspan, Heather B, et al.
Publicado: (2011)

An HIV Vaccine Protective Allele in FCGR2C Associates With Increased Odds of Perinatal HIV Acquisition
por: Ebonwu, Joy, et al.
Publicado: (2021)

Reduced CCR5 Expression and Immune Quiescence in Black South African HIV-1 Controllers
por: Picton, Anabela C. P., et al.
Publicado: (2021)

Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV – Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinical trial
por: Compagnucci, Alexandra, et al.
Publicado: (2023)

KIR-HLA and Maternal-Infant HIV-1 Transmission in Sub-Saharan Africa
por: Paximadis, Maria, et al.
Publicado: (2011)

Machine learning outperformed logistic regression classification even with limit sample size: A model to predict pediatric HIV mortality and clinical progression to AIDS
por: Domínguez-Rodríguez, Sara, et al.
Publicado: (2022)

Optimizing the World Health Organization algorithm for HIV vertical transmission risk assessment by adding maternal self-reported antiretroviral therapy adherence
por: Fernández-Luis, Sheila, et al.
Publicado: (2022)

P08-04. The role of class I HLA-B and HLA-Cw in disease progression and maternal-infant HIV-1 transmission in a South African population
por: Paximadis, M, et al.
Publicado: (2009)

Correction to: Deep sequencing of the HIV-1 polymerase gene for characterisation of cytotoxic T-lymphocyte epitopes during early and chronic disease stages
por: Nkone, Paballo, et al.
Publicado: (2022)

Deep sequencing of the HIV-1 polymerase gene for characterisation of cytotoxic T-lymphocyte epitopes during early and chronic disease stages
por: Nkone, Paballo, et al.
Publicado: (2022)

Evaluation of the HIV-1 Polymerase Gene Sequence Diversity for Prediction of Recent HIV-1 Infections Using Shannon Entropy Analysis
por: Nkone, Paballo, et al.
Publicado: (2022)

P08-02. Genetic variation within the gene encoding the HIV-1 CCR5 coreceptor in two South African population groups
por: Picton, AC, et al.
Publicado: (2009)

Promoting safe infant feeding practices – the importance of structural, social and contextual factors in Southern Africa
por: Lazarus, Ray, et al.
Publicado: (2013)

Once-daily dolutegravir-based antiretroviral therapy in infants and children living with HIV from age 4 weeks: results from the below 14 kg cohort in the randomised ODYSSEY trial
por: Amuge, Pauline, et al.
Publicado: (2022)

Genetic variation within the gene encoding the HIV-1 CCR5 coreceptor in two South African populations
por: Picton, Anabela C.P., et al.
Publicado: (2010)

Early Antiretroviral Therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy: Evidence from the Children with HIV Early Antiretroviral Therapy (CHER) Study
por: Hainline, Clotilde, et al.
Publicado: (2011)

FCGR3A gene duplication, FcγRIIb-232TT and FcγRIIIb-HNA1a associate with an increased risk of vertical acquisition of HIV-1
por: Ebonwu, Joy, et al.
Publicado: (2022)

Genetic Variability in Markers of HLA-C Expression in Two Diverse South African Populations
por: Gentle, Nikki L., et al.
Publicado: (2013)

Effect of Maternal HIV-1 Status and Antiretroviral Drugs on Haematological Profiles of South African Infants in Early Life
por: Schramm, Diana B, et al.
Publicado: (2010)

Virologic Response to Very Early HIV Treatment in Neonates
por: Shiau, Stephanie, et al.
Publicado: (2021)

The use of digit ratios as markers for perinatal androgen action
por: McIntyre, Matthew H
Publicado: (2006)

Healthy dynamics of CD4 T cells may drive HIV resurgence in perinatally-infected infants on antiretroviral therapy
por: Morris, Sinead E., et al.
Publicado: (2022)

Early ART Results in Greater Immune Reconstitution Benefits in HIV-Infected Infants: Working with Data Missingness in a Longitudinal Dataset
por: Azzoni, Livio, et al.
Publicado: (2015)

Implementation of a PMTCT programme in a high HIV prevalence setting in Johannesburg, South Africa: 2002–2015
por: Mnyani, Coceka N., et al.
Publicado: (2020)

Prevalence and Risk Factors for Hepatic Steatosis in Children With Perinatal HIV on Early Antiretroviral Therapy Compared to HIV-Exposed Uninfected and HIV-Unexposed Children
por: Rose, Penelope C., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4e5kn70pvulopurkuoqtru421s