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Identification of the novel role of butyrate as AhR ligand in human intestinal epithelial cells

The ligand activated transcription factor, aryl hydrocarbon receptor (AhR) emerged as a critical regulator of immune and metabolic processes in the gastrointestinal tract. In the gut, a main source of AhR ligands derives from commensal bacteria. However, many of the reported microbiota-derived ligan...

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Detalles Bibliográficos
Autores principales: Marinelli, Ludovica, Martin-Gallausiaux, Camille, Bourhis, Jean-Marie, Béguet-Crespel, Fabienne, Blottière, Hervé M., Lapaque, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345974/
https://www.ncbi.nlm.nih.gov/pubmed/30679727
http://dx.doi.org/10.1038/s41598-018-37019-2