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Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A(2)-like proteins using functional, structural and bioinformatics approaches

Ophidian accidents are considered an important neglected tropical disease by the World Health Organization. Particularly in Latin America, Bothrops snakes are responsible for the majority of the snakebite envenomings that are not efficiently treated by conventional serum therapy. Thus, the search fo...

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Detalles Bibliográficos
Autores principales: Salvador, Guilherme H. M., Cardoso, Fábio Florença, Gomes, Antoniel A., Cavalcante, Walter L. G., Gallacci, Márcia, Fontes, Marcos R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346006/
https://www.ncbi.nlm.nih.gov/pubmed/30679550
http://dx.doi.org/10.1038/s41598-018-36839-6