Antenatal Glucocorticoid Exposure Results in Sex-Specific and Transgenerational Changes in Prefrontal Cortex Gene Transcription that Relate to Behavioural Outcomes

Synthetic glucocorticoids (sGC) are administered to women at risk for pre-term delivery to reduce respiratory distress syndrome in the newborn. The prefrontal cortex (PFC) is important in regulating stress responses and related behaviours and expresses high levels of glucocorticoid receptors (GR). F...

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Detalles Bibliográficos
Autores principales: Constantinof, Andrea, Moisiadis, Vasilis G., Kostaki, Alisa, Szyf, Moshe, Matthews, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346022/
https://www.ncbi.nlm.nih.gov/pubmed/30679753
http://dx.doi.org/10.1038/s41598-018-37088-3

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